Genome-wide homozygosity in Example cutis laxa - cutis laxa

Click on a chromosome to zoom in.

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score	chr	from (bp)	to (bp)	from SNP	to SNP	build 36
broad - use this when you expect some genetic heterogeneity
160	12	115565378	125487124	rs953004	rs722704	region	genotypes
144	14	75063693	82796432	rs764187	rs2124851	region	genotypes
142	4	88969924	89938391	rs35491928	rs1377290	region	genotypes
135	12	126238381	126641435	rs950591	rs2013160	region	genotypes
132	15	37014936	45662565	rs1368800	rs718113	region	genotypes
131	4	93219460	99252883	rs1826058	rs1111541	region	genotypes
128	2	52254925	54138088	rs1922192	rs1363060	region	genotypes
narrow - use this when all patients are in the same family
160	12	115565378	125487124	rs953004	rs722704	region	genotypes
144	14	75063693	82796432	rs764187	rs2124851	region	genotypes
142	4	88969924	89938391	rs35491928	rs1377290	region	genotypes
135	12	126238381	126641435	rs950591	rs2013160	region	genotypes
132	15	37014936	45662565	rs1368800	rs718113	region	genotypes
131	4	93219460	99252883	rs1826058	rs1111541	region	genotypes
128	2	52254925	54138088	rs1922192	rs1363060	region	genotypes

change threshold

0.99 x max 0.9 x max 0.8 x max 0.7 x max 0.6 x max 0.5 x max

call GeneDistiller build 36

with all narrow broad regions at once

create files for Alohomora
flanking region [bp] allele frequencies from all samples allele frequencies from controls allele frequencies equally distributed narrow regions broad regions

create a BED file build 36
complete homozygous regions shown here		narrow regions broad regions
complete genes within these only exons	flanked by bases on each side.

analysis settings
project_name	Example cutis laxa	change name
analysis_name	cutis laxa	change name
analysis_description	PubMed
max_block_length	40
max_score	160
allele_frequencies	controls
user_login	examples
cases	8106,8107,8108,8109
controls	405-5491,407-5803

retrieve homozyosity scores
new & highly experimental: show this for build 36