GeneDistiller 2014

species		build		display online help (check this to see pop-up descriptions for each element)
order / prioritise genes

output as
NCBI synonyms	NCBI geneRIFs ( show only the first 10 geneRIFs)
Pathways (Reactome)	Transcripts (ENSEMBL) / ExonPrimer
Protein families (ENSEMBL)	Protein domains (InterPro)
Protein domains (PFAM)	Paralogs / sequence similarity (from ENSEMBL)
Pathways (Kegg)	Human Phenotype Ontology
OMIM reports ( show full reports)	MGD phenotypes ( show detailed descriptions)
Genbank files	GeneOntology terms
STRING interactions	Maestro score / mitochondria prediction
OrphaNet

linkage interval
chromosome	from	to
bp/Mbp (NCBI Build 37)
Values below 400 will be converted to Mbp. If (from) or (to) is not specified, the telomer will be used.
gene symbol
dbSNP ID / Affymetrix ID
microsatellite
type

single genes / gene lists
HGNC gene symbols / NCBI Entrez gene IDs Gene symbols and IDs must be comma-separated. * and % can be used as wildcards for gene symbols.
whole genome analysis	mitochondriome analysis
whole genome analysis	mitochondrial genes à la MitoCarta
known disease genes
OMIM IDs or keywords

		compare expression search for interactions
compare with these genes (Entrez gene ID / HGNC gene symbol)		(NCBI Gene ID or gene symbol; comma separated)
compare with these OMIM entries (ID or keyword)		(OMIM ID; comma separated)
limit to genes with a similar expression		cut-off value

highlight these...		show only genes...
highlight these keywords (OMIM/GeneRIFs)		with at least one of these words in their OMIM reports
highlight these HPO IDs (and their subclasses)		to which at least one of these HPO IDs applies
highlight these MGD phenotypes		to which at least one of these phenotypes was assigned
highlight these GO IDs (and their subclasses)		to which at least one of these GO IDs applies
highlight these Kegg pathways (specified by number)		involved in at least one of these Kegg pathways

Use these fields to fine-tune prioritisation according to your needs. When a prioritisation approach has been selected, default values will be filled in. You can change the values according to your needs and thus put more or less emphasis on the different parameters. When a weight is set to 0 (zero), the parameter will be ignored.
		Weight given to the...
Mitopred		Mitopred score for prediction of a mitochondrial import sequence
Maestro		Maestro score for prediction of a mitochondrial import sequence
OMIM title		occurence of a search term in an OMIM title
OMIM clinical symptoms		occurence of a search term in an OMIM clinical synposis
OMIM text		occurence of a search term in an OMIM report
NCBI geneRIFs		occurence of a search term in the NCBI GeneRIFs
MGD phenotype		existence of one of the selected MGD (Mouse Genome Database) phenotypes
successive MGD phenotype		existence of another selected MGD phenotype
HPO terms		existence of one of the specified Human Phenotype Ontology terms (or subclasses)
successive HPO terms		existence of another specified Human Phenotype Ontology terms (or subclasses)
expression similarity		expression similarity between the candidate gene and other gene(s) specified above under Comparison with known genes
tissue-specific expression		tissue-specific expression
cellular localisation		specified cellular, extracellular, or organellar localisation (or a sub-localisation thereof)
GO terms		existence of one of the specified GO (GeneOntology) terms (or subclasses)
successive GO terms		existence of another specified GO terms (or subclasses)
interaction		interaction with one of the specified partners (or partners selected by their OMIM disease phenotypes)
successive interaction		interaction with another of the specified partners
interaction, successive networks		interaction confirmed in another interaction network
PFAM		existence of a target PFAM domain
PFAM, successive domain		existence of another target PFAM domain
InterPro		existence of a target InterPro domain
InterPro, successive domain		existence of another target InterPro domain
Kegg pathways		member of a target pathway
Kegg, successive pathway		member of another target pathway
protein paralogs: identity		protein paralogs, weight of sequence identity

pigmentation phenotype
tumorigenesis
normal phenotype
no phenotypic analysis
nervous system phenotype
renal/urinary system phenotype
muscle phenotype
liver/biliary system phenotype
limbs/digits/tail phenotype
life span-post-weaning/aging
lethality-postnatal
lethality-embryonic/perinatal
adipose tissue phenotype
homeostasis/metabolism phenotype
hearing/vestibular/ear phenotype
growth/size phenotype
endocrine/exocrine gland phenotype
embryogenesis phenotype
digestive/alimentary phenotype
craniofacial phenotype
cellular phenotype
cardiovascular system phenotype
behaviour/neurological phenotype
immune system phenotype
respiratory system phenotype
reproductive system phenotype
skeleton phenotype
vision/eye phenotype
touch/vibrissae phenotype
skin/coat/nails phenotype
taste/olfaction phenotype
other phenotype
haematopoietic system phenotype